cGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholamine-dependent signaling in cardiac myocytes.
RATIONALE: cAMP and cGMP are intracellular second messengers involved in heart pathophysiology. cGMP can potentially affect cAMP signals via cGMP-regulated phosphodiesterases (PDEs). OBJECTIVE: To study the effect of cGMP signals on the local cAMP response to catecholamines in specific subcellular...
Prif Awduron: | Stangherlin, A, Gesellchen, F, Zoccarato, A, Terrin, A, Fields, L, Berrera, M, Surdo, N, Craig, M, Smith, G, Hamilton, G, Zaccolo, M |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2011
|
Eitemau Tebyg
-
cGMP-cAMP interplay in cardiac myocytes: a local affair with far-reaching consequences for heart function.
gan: Stangherlin, A, et al.
Cyhoeddwyd: (2012) -
Multi-compartment, early disruption of cGMP and cAMP signalling in cardiac myocytes from the mdx model of Duchenne Muscular Dystrophy
gan: Chao, Y-C, et al.
Cyhoeddwyd: (2020) -
Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors
gan: Gesellchen, F, et al.
Cyhoeddwyd: (2011) -
Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors.
gan: Gesellchen, F, et al.
Cyhoeddwyd: (2011) -
Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes
gan: Fields, L, et al.
Cyhoeddwyd: (2015)