cGMP signals modulate cAMP levels in a compartment-specific manner to regulate catecholamine-dependent signaling in cardiac myocytes.
RATIONALE: cAMP and cGMP are intracellular second messengers involved in heart pathophysiology. cGMP can potentially affect cAMP signals via cGMP-regulated phosphodiesterases (PDEs). OBJECTIVE: To study the effect of cGMP signals on the local cAMP response to catecholamines in specific subcellular...
Հիմնական հեղինակներ: | Stangherlin, A, Gesellchen, F, Zoccarato, A, Terrin, A, Fields, L, Berrera, M, Surdo, N, Craig, M, Smith, G, Hamilton, G, Zaccolo, M |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2011
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Նմանատիպ նյութեր
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cGMP-cAMP interplay in cardiac myocytes: a local affair with far-reaching consequences for heart function.
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Multi-compartment, early disruption of cGMP and cAMP signalling in cardiac myocytes from the mdx model of Duchenne Muscular Dystrophy
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cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology.
: Zaccolo, M, և այլն
Հրապարակվել է: (2007) -
Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes
: Fields, L, և այլն
Հրապարակվել է: (2015) -
Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors
: Gesellchen, F, և այլն
Հրապարակվել է: (2011)