MHC class II proteins and disease: a structural perspective.

MHC class II molecules on the surface of antigen-presenting cells display a range of peptides for recognition by the T-cell receptors of CD4+ T helper cells. Therefore, MHC class II molecules are central to effective adaptive immune responses, but conversely, genetic and epidemiological data have im...

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Bibliographic Details
Main Authors: Jones, E, Fugger, L, Strominger, J, Siebold, C
Format: Journal article
Language:English
Published: 2006