MHC class II proteins and disease: a structural perspective.
MHC class II molecules on the surface of antigen-presenting cells display a range of peptides for recognition by the T-cell receptors of CD4+ T helper cells. Therefore, MHC class II molecules are central to effective adaptive immune responses, but conversely, genetic and epidemiological data have im...
Auteurs principaux: | Jones, E, Fugger, L, Strominger, J, Siebold, C |
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Format: | Journal article |
Langue: | English |
Publié: |
2006
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