The histone deacetylase inhibitor romidepsin spares normal tissues while acting as an effective radiosensitiser in bladder tumours in vivo
<p><strong>Purpose:</strong><br /> Muscle-invasive bladder cancer has a 40% to 60% 5-year survival rate with radical treatment by surgical removal of the bladder or radiation therapy–based bladder preservation techniques, including concurrent chemoradiation. Elderly patients...
Main Authors: | Paillas, S, Then, C, Kilgas, S, Ruan, J, Thompson, J, Elliott, A, Smart, S, Kiltie, A |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2020
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