CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.

CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.

Hepatitis C virus infection is a major cause of chronic liver disease. CD4(+) T cells play a key role in disease outcome. However, the critical functions and associated phenotypes of intrahepatic CD4(+) T cells are not well defined. We have previously shown that CD8(+) T cells expressing the C type...

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Bibliographic Details
Main Authors: Kang, Y, Seigel, B, Bengsch, B, Fleming, V, Billerbeck, E, Simmons, R, Walker, L, Willberg, C, Barnes, E, Bhagwanani, A, Oo, Y, Blum, H, Adams, D, Thimme, R, Klenerman, P
Format: Journal article
Language:English
Published: 2012

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