Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men.
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these major histocompatibility complex (MHC) class II molecules have been developed to generate humanized models fo...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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| _version_ | 1797095316110966784 |
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| author | Fugger, L Svejgaard, A |
| author_facet | Fugger, L Svejgaard, A |
| author_sort | Fugger, L |
| collection | OXFORD |
| description | Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these major histocompatibility complex (MHC) class II molecules have been developed to generate humanized models for RA. The relevance of these models for understanding RA will be discussed. |
| first_indexed | 2024-03-07T04:26:08Z |
| format | Journal article |
| id | oxford-uuid:ccb0aba4-7675-4bb8-8e52-0eabfea28bf8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:26:08Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:ccb0aba4-7675-4bb8-8e52-0eabfea28bf82022-03-27T07:23:40ZAssociation of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ccb0aba4-7675-4bb8-8e52-0eabfea28bf8EnglishSymplectic Elements at Oxford2000Fugger, LSvejgaard, AInherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these major histocompatibility complex (MHC) class II molecules have been developed to generate humanized models for RA. The relevance of these models for understanding RA will be discussed. |
| spellingShingle | Fugger, L Svejgaard, A Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. |
| title | Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. |
| title_full | Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. |
| title_fullStr | Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. |
| title_full_unstemmed | Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. |
| title_short | Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. |
| title_sort | association of mhc and rheumatoid arthritis hla dr4 and rheumatoid arthritis studies in mice and men |
| work_keys_str_mv | AT fuggerl associationofmhcandrheumatoidarthritishladr4andrheumatoidarthritisstudiesinmiceandmen AT svejgaarda associationofmhcandrheumatoidarthritishladr4andrheumatoidarthritisstudiesinmiceandmen |