Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.
Pretreatment cytogenetics is a known predictor of outcome in hematologic malignancies. However, its usefulness in adult acute lymphoblastic leukemia (ALL) is generally limited to the presence of the Philadelphia (Ph) chromosome because of the low incidence of other recurrent abnormalities. We presen...
Autores principales: | Moorman, A, Harrison, C, Buck, G, Richards, S, Secker-Walker, L, Martineau, M, Vance, G, Cherry, A, Higgins, R, Fielding, A, Foroni, L, Paietta, E, Tallman, MS, Litzow, MR, Wiernik, P, Rowe, J, Goldstone, A, Dewald, G |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2007
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