No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5.

No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5.

Multiple sclerosis (MS) is a complex neurological disease with huge variability in disease outcome. The majority of MS genetic susceptibility is determined by major histocompatibility complex (MHC) alleles, in particular haplotypes carrying HLA-DRB1*1501. HLA-DRB1*1501 also affects the clinical outc...

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Detalhes bibliográficos
Main Authors:	Handel, A, De Luca, G, Morahan, J, Handunnetthi, L, Sadovnick, A, Ebers, G, Ramagopalan, S
Formato:	Journal article
Idioma:	English
Publicado em:	2010

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