Polycomb complexes in X chromosome inactivation

<p>Identifying the critical RNA binding proteins (RBPs) that elicit Xist mediated silencing has been a key goal in X inactivation research. Early studies implicated the Polycomb proteins, a family of factors linked to one of two major multiprotein complexes, PRC1 and PRC2 (Wang 2001 Nat. Genet...

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主要作者: Brockdorff, N
格式: Journal article
出版: Royal Society 2017