Of mice and men: is there a future for metformin in the treatment of hepatic steatosis?

Of mice and men: is there a future for metformin in the treatment of hepatic steatosis?

Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver diseases, of which the first stage is steatosis. It is one of the most common liver diseases in developed countries and there is a clear association between type 2 diabetes (T2DM) and NAFLD. It is estimated that 70% of people...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Green, C, Marjot, T, Tomlinson, J, Hodson, L
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Wiley 2018

समान संसाधन

Sodium-glucose cotransporter 2 inhibition does not reduce hepatic steatosis in overweight, insulin-resistant patients without type 2 diabetes
द्वारा: Marjot, T, और अन्य
प्रकाशित: (2019)

Metformin maintains intrahepatic triglyceride content through increased hepatic de novo lipogenesis
द्वारा: Green, CJ, और अन्य
प्रकाशित: (2022)

Sodium‐glucose cotransporter 2 inhibition does not reduce hepatic steatosis in overweight, insulin‐resistant patients without type 2 diabetes
द्वारा: Thomas Marjot, और अन्य
प्रकाशित: (2020-06-01)

Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)?
द्वारा: Tariq, Z, और अन्य
प्रकाशित: (2014)

Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)?
द्वारा: Tariq, Z, और अन्य
प्रकाशित: (2014)

Ginseng berry extract enhances metformin efficacy against obesity and hepatic steatosis in mice fed high-fat diet through increase of metformin uptake in liver
द्वारा: Hee-Sung Chae, और अन्य
प्रकाशित: (2019-11-01)

Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice
द्वारा: Sorim Choung, और अन्य
प्रकाशित: (2018-01-01)

Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity.
द्वारा: Shih-Lung Woo, और अन्य
प्रकाशित: (2014-01-01)

Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized Mice
द्वारा: Haeng Jeon Hur, और अन्य
प्रकाशित: (2020-10-01)

Comparison of Pioglitazone and Metformin Efficacy against Glucocorticoid Induced Atherosclerosis and Hepatic Steatosis in Insulin Resistant Rats
द्वारा: I M Nagendra Nayak, और अन्य
प्रकाशित: (2017-07-01)

Metformin Ameliorates Hepatic Steatosis induced by olanzapine through inhibiting LXRα/PCSK9 pathway
द्वारा: Wenqiang Zhu, और अन्य
प्रकाशित: (2022-04-01)

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet*
द्वारा: Mary E. Rinella, और अन्य
प्रकाशित: (2008-05-01)

Effects of bile acid sequestration on hepatic steatosis in obese mice
द्वारा: Nancy Solís, और अन्य
प्रकाशित: (2014-01-01)

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
द्वारा: Xiwen Xiong, और अन्य
प्रकाशित: (2019-01-01)

Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity
द्वारा: Frederique Van de Velde, और अन्य
प्रकाशित: (2020-01-01)

Non-alcoholic fatty liver disease in adults: Current concepts in etiology, outcomes and management
द्वारा: Marjot, T, और अन्य
प्रकाशित: (2019)

Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice
द्वारा: Shan Huang, और अन्य
प्रकाशित: (2021-08-01)

Incidental Hepatic Steatosis
द्वारा: Lawrence S. Friedman, और अन्य
प्रकाशित: (2023-01-01)

Genetic and hormonal control of hepatic steatosis in female and male mice1
द्वारा: Frode Norheim, और अन्य
प्रकाशित: (2017-01-01)

Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice.
द्वारा: Xin Guo, और अन्य
प्रकाशित: (2012-01-01)

Computed Tomography Measurement of Hepatic Steatosis: Prevalence of Hepatic Steatosis in a Canadian Population
द्वारा: Malcolm M. Wells, और अन्य
प्रकाशित: (2016-01-01)

Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice
द्वारा: Brecht Attema, और अन्य
प्रकाशित: (2022-12-01)

Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice
द्वारा: Nazmul Hasan, और अन्य
प्रकाशित: (2022-02-01)

Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance
द्वारा: Weiyu Chen, और अन्य
प्रकाशित: (2021-11-01)

TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in MiceSummary
द्वारा: Ling Yang, और अन्य
प्रकाशित: (2017-05-01)

Efficacy of Acetylshikonin in Preventing Obesity and Hepatic Steatosis in db/db Mice
द्वारा: Mei-Ling Su, और अन्य
प्रकाशित: (2016-07-01)

Effects of Metformin on Hepatic Steatosis in Adults with Nonalcoholic Fatty Liver Disease and Diabetes: Insights from the Cellular to Patient Levels
द्वारा: Kanokwan Pinyopornpanish, और अन्य
प्रकाशित: (2021-11-01)

Iron, hepatitis C virus and hepatic steatosis
द्वारा: J. A. Solís Herruzo, और अन्य

The efficacy of antiviral treatment in chronic hepatitis B patients with hepatic steatosis
द्वारा: Danqing Hu, और अन्य
प्रकाशित: (2024-04-01)

Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice
द्वारा: Valentina Volynets, और अन्य
प्रकाशित: (2010-12-01)

Similar insulin regulation of splanchnic FFA and VLDL-TG in men with nonalcoholic hepatic steatosis and steatohepatitis
द्वारा: Jeyanthini Risikesan, और अन्य
प्रकाशित: (2024-07-01)

PPAR𝛼 Is Required for PPAR𝛿 Action in Regulation of Body Weight and Hepatic Steatosis in Mice
द्वारा: Garbacz, Wojciech G., और अन्य
प्रकाशित: (2015)

Mechanistic studies of PEG-asparaginase-induced liver injury and hepatic steatosis in mice
द्वारा: Gundala Venkata Naveen Kumar, और अन्य
प्रकाशित: (2021-12-01)

Inflammatory Mediators of Hepatic Steatosis
द्वारा: Elizabeth Hijona, और अन्य
प्रकाशित: (2010-01-01)

Recognition of Diffuse Hepatic Steatosis
द्वारा: Danil Yevdokimov, और अन्य
प्रकाशित: (2023-05-01)

Hepatic steatosis in patients with acromegaly
द्वारा: Andreani Koutsou‐Tassopoulou, और अन्य
प्रकाशित: (2019-10-01)

Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR −/− mice
द्वारा: Ganesan Murali, और अन्य
प्रकाशित: (2012-10-01)

Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis
द्वारा: Gunn, P, और अन्य
प्रकाशित: (2020)

Hepatic steatosis and its relationship to transplantation.
द्वारा: Imber, C, और अन्य
प्रकाशित: (2002)

Short-Term Metformin Treatment Enriches Bacteroides dorei in an Obese Liver Steatosis Zucker Rat Model
द्वारा: Michael S. Robeson, और अन्य
प्रकाशित: (2022-03-01)