Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia
Non-genetic mechanisms of transformation are still relatively understudied and poorly understood. In this issue of Cell Stem Cell, Muto et al. provide preclinical evidence that loss of TRAF6 expression promotes transformation through a MYC-dependent mechanism that may be modulated by environmental i...
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| Format: | Journal article |
| Language: | English |
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Elsevier
2022
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| _version_ | 1797108711903199232 |
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| author | Vyas, P |
| author_facet | Vyas, P |
| author_sort | Vyas, P |
| collection | OXFORD |
| description | Non-genetic mechanisms of transformation are still relatively understudied and poorly understood. In this issue of Cell Stem Cell, Muto et al. provide preclinical evidence that loss of TRAF6 expression promotes transformation through a MYC-dependent mechanism that may be modulated by environmental inflammatory signals. |
| first_indexed | 2024-03-07T07:32:31Z |
| format | Journal article |
| id | oxford-uuid:cd4ba335-9519-40b4-8d87-989b1abbbf22 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:32:31Z |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:cd4ba335-9519-40b4-8d87-989b1abbbf222023-02-03T09:14:32ZGenetic and non-genetic mechanisms of inflammation may promote transformation in leukemiaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:cd4ba335-9519-40b4-8d87-989b1abbbf22EnglishSymplectic ElementsElsevier2022Vyas, PNon-genetic mechanisms of transformation are still relatively understudied and poorly understood. In this issue of Cell Stem Cell, Muto et al. provide preclinical evidence that loss of TRAF6 expression promotes transformation through a MYC-dependent mechanism that may be modulated by environmental inflammatory signals. |
| spellingShingle | Vyas, P Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia |
| title | Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia |
| title_full | Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia |
| title_fullStr | Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia |
| title_full_unstemmed | Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia |
| title_short | Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia |
| title_sort | genetic and non genetic mechanisms of inflammation may promote transformation in leukemia |
| work_keys_str_mv | AT vyasp geneticandnongeneticmechanismsofinflammationmaypromotetransformationinleukemia |