Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.
Localized clustering of damage is a hallmark of certain DNA-damaging agents, particularly ionizing radiation. The potential for genetic change arising from the effects of clustered damage sites containing combinations of AP sites, 8-oxo-7,8-dihydroguanine (8-oxoG) or 5,6-dihydrothymine is high. To d...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Oxford University Press
2009
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