Analysis of adhesive domains from the A4VAR Plasmodium falciparum erythrocyte membrane protein-1 identifies a CD36 binding domain.
The A4VAR is a variant antigen expressed by a clonal line that binds CD36 and intercellular adhesion molecule-1, ICAM-1. We have cloned and sequenced the extracellular domain coded by the A4var gene. To probe the relationship between A4var expression and parasite adhesion to ICAM-1, var mRNA and pro...
Հիմնական հեղինակներ: | Smith, J, Kyes, S, Craig, A, Fagan, T, Hudson-Taylor, D, Miller, L, Baruch, D, Newbold, C |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
1998
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Նմանատիպ նյութեր
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Var gene diversity in Plasmodium falciparum is generated by frequent recombination events.
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