Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy

Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy

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Background Androgen-deprivation therapy (ADT) is standard treatment for locally advanced or metastatic prostate cancer (PCa). Many patients develop castration resistance (castration-resistant PCa [CRPC]) after approximately 2-3 yr, with a poor prognosis. The molecular mechanisms underlying CRPC prog...

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Huvudupphovsmän: Rajan, P, Sudbery, I, Villasevil, M, Mui, E, Fleming, J, Davis, M, Ahmad, I, Edwards, J, Sansom, O, Sims, D, Ponting, C, Heger, A, McMenemin, R, Pedley, I, Leung, H
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2014

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