Investigating the PIP2 Binding Site in Kir Channels Via Multi-Scale Biomolecular Simulations

Investigating the PIP2 Binding Site in Kir Channels Via Multi-Scale Biomolecular Simulations

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Stansfeld, P, Hopkinson, R, Ashcroft, F, Sansom, M
التنسيق:	Journal article
منشور في:	2010

مواد مشابهة

PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.
حسب: Stansfeld, P, وآخرون
منشور في: (2009)

PIP2-binding site in Kir channels: definition by multiscale biomolecular simulations
حسب: Stansfeld, P, وآخرون
منشور في: (2009)

Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.
حسب: Haider, S, وآخرون
منشور في: (2007)

Ion-blocking sites of the Kir2.1 channel revealed by multiscale modeling.
حسب: Tai, K, وآخرون
منشور في: (2009)

Simulating PIP2-Induced Gating Transitions in Kir6.2 Channels
حسب: Michael Bründl, وآخرون
منشور في: (2021-08-01)

Identification of residues contributing to the ATP binding site of Kir6.2.
حسب: Trapp, S, وآخرون
منشور في: (2003)

Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.
حسب: Antcliff, J, وآخرون
منشور في: (2005)

Conformational rearrangements during PIP2 gating in Kir channels
حسب: Rapedius, M, وآخرون
منشور في: (2007)

Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.
حسب: Dabrowski, M, وآخرون
منشور في: (2004)

Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.
حسب: Haider, S, وآخرون
منشور في: (2005)

Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing.
حسب: Rapedius, M, وآخرون
منشور في: (2007)

Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.
حسب: Haider, S, وآخرون
منشور في: (2007)

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface
حسب: Camden M. Driggers, وآخرون
منشور في: (2024-03-01)

Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2
حسب: Avia Rosenhouse-Dantsker, وآخرون
منشور في: (2014-09-01)

Mapping the architecture of the ATP-binding site of Kir6.2
حسب: Dabrowski, M, وآخرون
منشور في: (2002)

Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.
حسب: Capener, C, وآخرون
منشور في: (2003)

A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated.
حسب: Männikkö, R, وآخرون
منشور في: (2011)

Ion channels - Exciting times for PIP2
حسب: Ashcroft, F
منشور في: (1998)

A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.
حسب: Tammaro, P, وآخرون
منشور في: (2007)

Andersen–Tawil Syndrome Is Associated With Impaired PIP2 Regulation of the Potassium Channel Kir2.1
حسب: Reem Handklo-Jamal, وآخرون
منشور في: (2020-05-01)

Modulation of the IKS channel by PIP2 requires two binding sites per monomer
حسب: Audrey Deyawe Kongmeneck, وآخرون
منشور في: (2023-01-01)

Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.
حسب: Haider, S, وآخرون
منشور في: (2005)

Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.
حسب: Schmidt, MR, وآخرون
منشور في: (2013)

Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.
حسب: Jones, P, وآخرون
منشور في: (2001)

Time-dependent activation of Kir6.2/SUR2A channels but not Kir6.2/SUR1 channels in the presence of ATP
حسب: Ashcroft, F, وآخرون
منشور في: (2001)

Time-dependent activation of KIR6.2/SUR2A channels but not KIR6.2/SUR1 channels in the presence of MgATP
حسب: Song, D, وآخرون
منشور في: (2001)

Glimepiride block of Kir6.2/SUR1 Kir6.2/SUR2A and Kir6.2/SUR2A and Kir6.2/SUR2B K-ATP channels.
حسب: Ashcroft, F, وآخرون
منشور في: (2001)

Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.
حسب: Hansen, A, وآخرون
منشور في: (2005)

Phentolamine block of KATP channels is mediated by Kir6.2.
حسب: Proks, P, وآخرون
منشور في: (1997)

Computer modelling and simulation studies of a human inwardly rectifying potassium channel Kir6.2
حسب: Capener, C, وآخرون
منشور في: (2000)

Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations.
حسب: Grottesi, A, وآخرون
منشور في: (2005)

Exciting times for PIP2.
حسب: Ashcroft, F
منشور في: (1998)

PIP2 and PIP as determinants for ATP inhibition of KATP channels.
حسب: Baukrowitz, T, وآخرون
منشور في: (1998)

K2P and Kir K+ Channels in Physiological Bilayers
حسب: Schmidt, MR, وآخرون
منشور في: (2013)

Membrane recognition and binding by the phosphatidylinositol phosphate kinase PIP5K1A: a multiscale simulation study
حسب: Amos, S-BTA, وآخرون
منشور في: (2019)

Quality assurance for biomolecular simulations
حسب: Murdock, SE, وآخرون
منشور في: (2006)

Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel.
حسب: Reimann, F, وآخرون
منشور في: (2001)

Permeation and gating in KirBac: Molecular dynamics simulations
حسب: Grottesi, A, وآخرون
منشور في: (2004)

Grid computing and biomolecular simulation.
حسب: Woods, C, وآخرون
منشور في: (2005)

Filter flexibility and distortion in a bacterial inward rectifier K+ channel: simulation studies of KirBac1.1.
حسب: Domene, C, وآخرون
منشور في: (2004)