Dearomatisation of o-xylene by P450BM3 (CYP102A1).

The oxidation of o-xylene by P450(BM3) from Bacillus megaterium yields, in addition to the products formed by microsomal P450s, two metabolites containing an NIH-shifted methyl group, one of which lacks the aromatic character of the substrate. The failure of the epoxide precursor of these two produc...

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Bibliographic Details
Main Authors: Whitehouse, C, Rees, N, Bell, S, Wong, L
Format: Journal article
Language:English
Published: 2011