Autonomous roles for the cytoplasmic domains of the CD2 and CD4 T cell surface antigens.
CD2 and CD4 are single chain transmembrane T cell surface molecules that are involved in signal transduction. Chimaeric constructs from rat CD2 and CD4 antigens were expressed in the Jurkat human T cell line to examine the role of extracellular, transmembrane and cytoplasmic domains in mediating fun...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1991
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