Autonomous roles for the cytoplasmic domains of the CD2 and CD4 T cell surface antigens.

CD2 and CD4 are single chain transmembrane T cell surface molecules that are involved in signal transduction. Chimaeric constructs from rat CD2 and CD4 antigens were expressed in the Jurkat human T cell line to examine the role of extracellular, transmembrane and cytoplasmic domains in mediating fun...

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Bibliographic Details
Main Authors: Beyers, A, Davis, S, Cantrell, D, Izquierdo, M, Williams, A
Format: Journal article
Language:English
Published: 1991