A novel murine cytomegalovirus vaccine vector protects against Mycobacterium tuberculosis.

Tuberculosis remains a global health problem so that a more effective vaccine than bacillus Calmette-Guérin is urgently needed. Cytomegaloviruses persist lifelong in vivo and induce powerful immune and increasing ("inflationary") responses, making them attractive vaccine vectors. We have u...

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Main Authors: Beverley, P, Ruzsics, Z, Hey, A, Hutchings, C, Boos, S, Bolinger, B, Marchi, E, O'Hara, G, Klenerman, P, Koszinowski, U, Tchilian, E
Format: Journal article
Jezik:English
Izdano: American Association of Immunologists 2014