Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.

Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.

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Many anticancer therapies, including ionizing radiation (IR), cause cytotoxicity through generation of DNA double-strand breaks (DSB). Delivery of therapeutic radionuclides to DNA DSB sites can amplify this DNA damage, for additional therapeutic gain. Herein, we report on two radiopharmaceuticals, r...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Cornelissen, B, Waller, A, Able, S, Vallis, K
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	American Association for Cancer Research 2013

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