A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations.

BACKGROUND: β-Microseminoprotein (MSP) is one of the three most abundantly secreted proteins of the prostate and has been suggested as a biomarker for prostate cancer risk. A common variant, rs10993994, in the 5' region of the gene that encodes MSP (MSMB) has recently been identified as a risk...

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Détails bibliographiques
Auteurs principaux: Waters, K, Stram, DO, Le Marchand, L, Klein, R, Valtonen-André, C, Peltola, M, Kolonel, L, Henderson, B, Lilja, H, Haiman, C
Format: Journal article
Langue:English
Publié: 2010