The talin FERM domain is not so FERM

The structure of the head domain of talin, an intracellular activator of integrin membrane adhesion receptors, has been solved by Elliott et al. (2010). A FERM domain can be identified in the head from sequence comparisons but, rather than having a compact structure of three subdomains, it has linea...

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Detalles Bibliográficos
Autor Principal: Campbell, I
Formato: Journal article
Idioma:English
Publicado: 2010
Descripción
Summary:The structure of the head domain of talin, an intracellular activator of integrin membrane adhesion receptors, has been solved by Elliott et al. (2010). A FERM domain can be identified in the head from sequence comparisons but, rather than having a compact structure of three subdomains, it has linear arrangement of four subdomains. © 2010 Elsevier Ltd.