Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.

Depression is common in people with schizophrenia, but how it might directly contribute to the persistence of psychotic symptoms has rarely been tested. The key aim of the present study was to test whether depression and associated cognitive processes predict the maintenance of persecutory delusions...

Full description

Bibliographic Details
Main Authors: Vorontsova, N, Garety, P, Freeman, D
Format: Journal article
Language:English
Published: 2013
_version_ 1826297339463073792
author Vorontsova, N
Garety, P
Freeman, D
author_facet Vorontsova, N
Garety, P
Freeman, D
author_sort Vorontsova, N
collection OXFORD
description Depression is common in people with schizophrenia, but how it might directly contribute to the persistence of psychotic symptoms has rarely been tested. The key aim of the present study was to test whether depression and associated cognitive processes predict the maintenance of persecutory delusions. Three groups of participants were tested at baseline: 60 patients with persecutory delusions in the context of a schizophrenia spectrum diagnosis, 30 patients with depression, and 30 nonclinical controls. They completed interviewer and self-report assessments of depression and paranoia, and measures of six cognitive factors (schematic beliefs, experiential avoidance, autobiographical memory, problem solving, rumination, worry style). The patients with persecutory delusions were then assessed again, six months later. It was found that 50% of the patients with persecutory delusions met diagnostic criteria for major depression. Cognitive processes found to be associated with depression across the groups were negative schematic beliefs about the self, experiential avoidance and rumination, but not autobiographical memory or problem solving. The severity of initial depression in patients with persecutory delusions predicted the persistence of paranoia over six months. A number of cognitive factors also predicted the persistence of persecutory delusions, including negative schematic beliefs about the self, worry, and problem-solving difficulties. In conclusion, depression is common in patients with current persecutory delusions, and it shows similar cognitive features to major depressive disorder. The results of this study indicate that depression and related processes may contribute to the maintenance of paranoia. Trials are warranted of depression-related therapeutic techniques for people with persecutory delusions.
first_indexed 2024-03-07T04:30:05Z
format Journal article
id oxford-uuid:cdfd6854-c570-4bc7-bde0-14d66aa0a377
institution University of Oxford
language English
last_indexed 2024-03-07T04:30:05Z
publishDate 2013
record_format dspace
spelling oxford-uuid:cdfd6854-c570-4bc7-bde0-14d66aa0a3772022-03-27T07:32:45ZCognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:cdfd6854-c570-4bc7-bde0-14d66aa0a377EnglishSymplectic Elements at Oxford2013Vorontsova, NGarety, PFreeman, DDepression is common in people with schizophrenia, but how it might directly contribute to the persistence of psychotic symptoms has rarely been tested. The key aim of the present study was to test whether depression and associated cognitive processes predict the maintenance of persecutory delusions. Three groups of participants were tested at baseline: 60 patients with persecutory delusions in the context of a schizophrenia spectrum diagnosis, 30 patients with depression, and 30 nonclinical controls. They completed interviewer and self-report assessments of depression and paranoia, and measures of six cognitive factors (schematic beliefs, experiential avoidance, autobiographical memory, problem solving, rumination, worry style). The patients with persecutory delusions were then assessed again, six months later. It was found that 50% of the patients with persecutory delusions met diagnostic criteria for major depression. Cognitive processes found to be associated with depression across the groups were negative schematic beliefs about the self, experiential avoidance and rumination, but not autobiographical memory or problem solving. The severity of initial depression in patients with persecutory delusions predicted the persistence of paranoia over six months. A number of cognitive factors also predicted the persistence of persecutory delusions, including negative schematic beliefs about the self, worry, and problem-solving difficulties. In conclusion, depression is common in patients with current persecutory delusions, and it shows similar cognitive features to major depressive disorder. The results of this study indicate that depression and related processes may contribute to the maintenance of paranoia. Trials are warranted of depression-related therapeutic techniques for people with persecutory delusions.
spellingShingle Vorontsova, N
Garety, P
Freeman, D
Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.
title Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.
title_full Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.
title_fullStr Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.
title_full_unstemmed Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.
title_short Cognitive factors maintaining persecutory delusions in psychosis: the contribution of depression.
title_sort cognitive factors maintaining persecutory delusions in psychosis the contribution of depression
work_keys_str_mv AT vorontsovan cognitivefactorsmaintainingpersecutorydelusionsinpsychosisthecontributionofdepression
AT garetyp cognitivefactorsmaintainingpersecutorydelusionsinpsychosisthecontributionofdepression
AT freemand cognitivefactorsmaintainingpersecutorydelusionsinpsychosisthecontributionofdepression