Decreased STARD10 expression is associated with defective insulin secretion in humans and mice.

Decreased STARD10 expression is associated with defective insulin secretion in humans and mice.

Бусад хувилбаруудыг харуулах (1)

Genetic variants near ARAP1 (CENTD2) and STARD10 influence type 2 diabetes (T2D) risk. The risk alleles impair glucose-induced insulin secretion and, paradoxically but characteristically, are associated with decreased proinsulin:insulin ratios, indicating improved proinsulin conversion. Neither the...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Carrat, G, Hu, M, Nguyen-Tu, M, Chabosseau, P, Gaulton, K, van de Bunt, M, Siddiq, A, Falchi, M, Thurner, M, Canouil, M, Pattou, F, Leclerc, I, Pullen, T, Cane, M, Prabhala, P, Greenwald, W, Schulte, A, Marchetti, P, Ibberson, M, MacDonald, P, Manning Fox, J, Gloyn, A, Froguel, P, Solimena, M, McCarthy, M, Rutter, G
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Elsevier 2017

Ижил төстэй зүйлс

Decreased STARD10 expression is associated with defective insulin secretion in humans and mice
-н: Carrat, G, зэрэг
Хэвлэсэн: (2017)

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis
-н: Carrat, GR, зэрэг
Хэвлэсэн: (2020)

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β cell are associated with glucose intolerance in humans and mice
-н: Mehta, Z, зэрэг
Хэвлэсэн: (2016)

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.
-н: Mehta, Z, зэрэг
Хэвлэсэн: (2016)

[Diagnostic (STARD) and prognostic (REMARK) studies].
-н: Altman, D, зэрэг
Хэвлэсэн: (2005)

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

The STARD initiative for reporting of studies of diagnostic accuracy: Explanation and comments
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data
-н: Fernández-Tajes, J, зэрэг
Хэвлэсэн: (2019)

Updating standards for reporting diagnostic accuracy: the development of STARD 2015
-н: Korevaar, D, зэрэг
Хэвлэсэн: (2016)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Toward complete and accurate reporting of studies of diagnostic accuracy. The STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2007)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2004)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Toward complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Erratum: Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2011)

STARD 2015 guidelines for reporting diagnostic accuracy studies: Explanation and elaboration
-н: Cohen, J, зэрэг
Хэвлэсэн: (2016)

STARD 2015: An updated list of essential items for reporting diagnostic accuracy studies.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2015)

STARD 2015: An updated list of essential items for reporting diagnostic accuracy studies.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2015)

STARD for Abstracts: essential items for reporting diagnostic accuracy studies in journal or conference abstracts
-н: Cohen, J, зэрэг
Хэвлэсэн: (2017)

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis
-н: Van De Bunt, M, зэрэг
Хэвлэсэн: (2013)

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. The Standards for Reporting of Diagnostic Accuracy Group.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

[Reporting studies of diagnostic accuracy according to a standard method; the Standards for Reporting of Diagnostic Accuracy (STARD)].
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic Accuracy.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. The Standards for Reporting of Diagnostic Accuracy Group.
-н: Bossuyt, P, зэрэг
Хэвлэсэн: (2003)

A tale of two glucose transporters: how GLUT2 re-emerged as a contender for glucose transport into the human beta cell.
-н: van de Bunt, M, зэрэг
Хэвлэсэн: (2012)

A tale of two glucose transporters: How GLUT2 re-emerged as a contender for glucose transport into the human beta cell
-н: Van De Bunt, M, зэрэг
Хэвлэсэн: (2012)

From genetic association to molecular mechanism.
-н: van de Bunt, M, зэрэг
Хэвлэсэн: (2010)

Monogenic disorders of the pancreatic β-cell: Personalizing treatment for rare forms of diabetes and hypoglycemia
-н: van de Bunt, M, зэрэг
Хэвлэсэн: (2007)

Developing a reporting guideline for artificial intelligence-centred diagnostic test accuracy studies: the STARD-AI protocol
-н: Sounderajah, V, зэрэг
Хэвлэсэн: (2021)

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
-н: Thurner, M, зэрэг
Хэвлэсэн: (2018)

The role of novel genetic and epigenetic mechanisms in the development of type 2 diabetes
-н: Thurner, M
Хэвлэсэн: (2016)

Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo
-н: Salem, V, зэрэг
Хэвлэсэн: (2019)