Continuous subcutaneous growth hormone releasing factor analogue augments growth hormone secretion in normal male subjects with no desensitization of the somatotroph.
The effects of 8 day continuous subcutaneous (s.c.) infusions of growth hormone releasing hormone analogue (NLE27GRF(1-29)NH2 (GHRH.A)) on growth hormone (GH) secretion were studied in 14 normal adult male volunteers. GHRH.A was administered in doses which ranged from 7.5 to 120 ng/kg/min in doublin...
Main Authors: | Brain, C, Hindmarsh, P, Brook, C, Matthews, DR |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1988
|
Similar Items
-
The effect of repeated administration of hexarelin, a growth hormone releasing peptide, and growth hormone releasing hormone on growth hormone responsivity.
by: Massoud, A, et al.
Published: (1996) -
The interaction of growth hormone releasing hormone and somatostatin in the generation of a GH pulse in man.
by: Hindmarsh, P, et al.
Published: (1991) -
CALCULATION OF PITUITARY GROWTH-HORMONE (GH) SECRETION RATE IN CHILDREN
by: Hindmarsh, P, et al.
Published: (1988) -
The application of deconvolution analysis to elucidate the pulsatile nature of growth hormone secretion using a variable half-life of growth hormone.
by: Hindmarsh, P, et al.
Published: (1990) -
The pituitary gland is capable of responding to two successive doses of growth hormone releasing hormone (GHRH)
by: Suri, D, et al.
Published: (1991)