Renal prostaglandin synthesis in experimental renal clip hypertension in the rat.
1. The hypothesis that suppression of prostaglandin E (PGE) synthesis by indomethacin exacerbates renal clip hypertension in the rat was investigated. 2. Indomethacin exacerbated hypertension in renal clip rats. 3. In vitro PGE synthesis determined by gas liquid chromatography (GLC) was suppressed i...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1976
|
| _version_ | 1797095625660039168 |
|---|---|
| author | Pugsley, D Beilin, L Peto, R |
| author_facet | Pugsley, D Beilin, L Peto, R |
| author_sort | Pugsley, D |
| collection | OXFORD |
| description | 1. The hypothesis that suppression of prostaglandin E (PGE) synthesis by indomethacin exacerbates renal clip hypertension in the rat was investigated. 2. Indomethacin exacerbated hypertension in renal clip rats. 3. In vitro PGE synthesis determined by gas liquid chromatography (GLC) was suppressed in medullary tissue from the hypertensive animals irrespective of indomethacin treatment. 4. The findings support the concept that PGs participate in blood pressure regulation in experimental renal hypertension. |
| first_indexed | 2024-03-07T04:30:33Z |
| format | Journal article |
| id | oxford-uuid:ce263ff2-ff89-4cb7-8b3c-419b59189958 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:30:33Z |
| publishDate | 1976 |
| record_format | dspace |
| spelling | oxford-uuid:ce263ff2-ff89-4cb7-8b3c-419b591899582022-03-27T07:33:47ZRenal prostaglandin synthesis in experimental renal clip hypertension in the rat.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ce263ff2-ff89-4cb7-8b3c-419b59189958EnglishSymplectic Elements at Oxford1976Pugsley, DBeilin, LPeto, R1. The hypothesis that suppression of prostaglandin E (PGE) synthesis by indomethacin exacerbates renal clip hypertension in the rat was investigated. 2. Indomethacin exacerbated hypertension in renal clip rats. 3. In vitro PGE synthesis determined by gas liquid chromatography (GLC) was suppressed in medullary tissue from the hypertensive animals irrespective of indomethacin treatment. 4. The findings support the concept that PGs participate in blood pressure regulation in experimental renal hypertension. |
| spellingShingle | Pugsley, D Beilin, L Peto, R Renal prostaglandin synthesis in experimental renal clip hypertension in the rat. |
| title | Renal prostaglandin synthesis in experimental renal clip hypertension in the rat. |
| title_full | Renal prostaglandin synthesis in experimental renal clip hypertension in the rat. |
| title_fullStr | Renal prostaglandin synthesis in experimental renal clip hypertension in the rat. |
| title_full_unstemmed | Renal prostaglandin synthesis in experimental renal clip hypertension in the rat. |
| title_short | Renal prostaglandin synthesis in experimental renal clip hypertension in the rat. |
| title_sort | renal prostaglandin synthesis in experimental renal clip hypertension in the rat |
| work_keys_str_mv | AT pugsleyd renalprostaglandinsynthesisinexperimentalrenalcliphypertensionintherat AT beilinl renalprostaglandinsynthesisinexperimentalrenalcliphypertensionintherat AT petor renalprostaglandinsynthesisinexperimentalrenalcliphypertensionintherat |