The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design.

OBJECTIVE: Developing a vaccine that is cross-reactive between HCV genotypes requires data on T cell antigenic targets that extends beyond genotype-1. We characterised T cell immune responses against HCV genotype-3, the most common infecting genotype in the UK and Asia, and assessed within genotype...

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Main Authors: von Delft, A, Humphreys, I, Brown, A, Pfafferott, K, Lucas, M, Klenerman, P, Lauer, G, Cox, A, Gaudieri, S, Barnes, E
格式: Journal article
语言:English
出版: 2015