Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial.

Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial.

Zobrazit další vydání (1)

BACKGROUND: Primaquine is the only available drug that clears mature Plasmodium falciparum gametocytes in infected human hosts, thereby preventing transmission of malaria to mosquitoes. However, concerns about dose-dependent haemolysis in people with glucose-6-phosphate dehydrogenase (G6PD) deficien...

Podrobná bibliografie
Hlavní autoři:	Eziefula, A, Bousema, T, Yeung, S, Kamya, M, Owaraganise, A, Gabagaya, G, Bradley, J, Grignard, L, Lanke, K, Wanzira, H, Mpimbaza, A, Nsobya, S, White, N, Webb, E, Staedke, S, Drakeley, C
Médium:	Journal article
Jazyk:	English
Vydáno:	Elsevier 2014

Podobné jednotky

Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial
Autor: Eziefula, A, a další
Vydáno: (2014)

Single dose primaquine for clearance of Plasmodium falaparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial
Autor: Eziefula, A, a další
Vydáno: (2014)

Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda
Autor: Eziefula, A, a další
Vydáno: (2013)

Efficacy of single dose primaquine with artemisinin combination therapy on P. falciparum gametocytes and transmission: A WWARN individual patient meta-analysis
Autor: Stepniewska, K, a další
Vydáno: (2020)

Editorial commentary: single-dose primaquine as gametocytocidal treatment in patients with uncomplicated falciparum malaria.
Autor: Dondorp, A
Vydáno: (2013)

Sustained efficacy of artesunate-sulfadoxine-pyrimethamine against Plasmodium falciparum in Yemen and a renewed call for an adjunct single dose primaquine to clear gametocytes
Autor: Atroosh, W.M., a další
Vydáno: (2016)

Antibody responses to crude gametocyte extract predict plasmodium falciparum gametocyte carriage in Kenya
Autor: Omondi, BR, a další
Vydáno: (2020)

Risk factors for gametocyte carriage in uncomplicated falciparum malaria.
Autor: Price, R, a další
Vydáno: (1999)

Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes
Autor: Chiara Andolina, a další
Vydáno: (2024-03-01)

Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis
Autor: Commons, RJ, a další
Vydáno: (2023)

Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo
Autor: Onyamboko, MA, a další
Vydáno: (2023)

Primaquine dose and the risk of haemolysis in patients with uncomplicated Plasmodium vivax malaria: a systematic review and individual patient data meta-analysis
Autor: Rajasekhar, M, a další
Vydáno: (2023)

The effect of single low-dose primaquine treatment for uncomplicated Plasmodium falciparum malaria on haemoglobin levels in Ethiopia: a longitudinal cohort study
Autor: Kassahun Habtamu, a další
Vydáno: (2024-07-01)

Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial
Autor: Dicko, A, a další
Vydáno: (2016)

An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia
Autor: Leang, R, a další
Vydáno: (2016)

Higher-dose primaquine to prevent relapse of Plasmodium vivax malaria
Autor: Watson, JA, a další
Vydáno: (2022)

Erratum to: An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia
Autor: Leang, R, a další
Vydáno: (2016)

Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data
Autor: Stepniewska, K, a další
Vydáno: (2022)

High-dose primaquine regimens against relapse of Plasmodium vivax malaria.
Autor: Krudsood, S, a další
Vydáno: (2008)

A randomised controlled trial to compare the efficacy, safety, and tolerability of low dose, short course primaquine in adults with uncomplicated P. vivax malaria in two hospitals in India
Autor: Ahmad, SS, a další
Vydáno: (2024)

A randomised controlled trial to compare the efficacy, safety, and tolerability of low dose, short course primaquine in adults with uncomplicated P. vivax malaria in two hospitals in India
Autor: Sundus Shafat Ahmad, a další
Vydáno: (2024-02-01)

Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malaria
Autor: Mukaka, M, a další
Vydáno: (2023)

Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria
Autor: Taylor, WR, a další
Vydáno: (2021)

Plasmodium falciparum gametocyte production correlates with genetic markers of parasite replication but is not influenced by experimental exposure to mosquito bitingResearch in context
Autor: Sara Lynn Blanken, a další
Vydáno: (2024-07-01)

Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
Autor: Das, D, a další
Vydáno: (2013)

Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: A systematic review and meta-analysis of individual patient data
Autor: Abdulla, S, a další
Vydáno: (2016)

Gametocyte carriage in uncomplicated plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data
Autor: Abdulla, S, a další
Vydáno: (2016)

Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: a multi-national study
Autor: O'Flaherty, K, a další
Vydáno: (2022)

Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity.
Autor: Stepniewska, K, a další
Vydáno: (2008)

Single dose artemisinin-mefloquine treatment for acute uncomplicated falciparum malaria.
Autor: Tran, T, a další
Vydáno: (1994)

Clinical trial of oral artesunate with or without high-dose primaquine for the treatment of vivax malaria in Thailand.
Autor: Silachamroon, U, a další
Vydáno: (2003)

Mechanisms of lymphoma clearance induced by high-dose alkylating agents
Autor: Lossos, Chen, a další
Vydáno: (2021)

The tolerability of single low dose primaquine in glucose-6-phosphate deficient and normal falciparum-infected Cambodians
Autor: Dysoley, L, a další
Vydáno: (2019)

Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial.
Autor: Smithuis, F, a další
Vydáno: (2010)

Primaquine phosphate (primaquine diphosphate)
Autor: 982 SIRIM

Chloroquine-primaquine therapeutic response and safety in patients with uncomplicated Plasmodium vivax malaria in the Colombian Amazon region
Autor: Paula Calderón-Ruiz, a další
Vydáno: (2024-11-01)

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers
Autor: Sasithon Pukrittayakamee, a další
Vydáno: (2024-02-01)

Immune responses to gametocyte antigens in a malaria endemic population—the African falciparum context: a systematic review and meta-analysis
Autor: Muthui, MK, a další
Vydáno: (2019)

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers
Autor: Pukrittayakamee, S, a další
Vydáno: (2024)

Slow clearance of histidine-rich protein-2 in Gabonese with uncomplicated malaria
Autor: Carlos Lamsfus Calle, a další
Vydáno: (2024-10-01)