Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1.

The adhesion of Plasmodium falciparum-infected erythrocytes is thought to play a central role in the pathogenesis of severe malaria. ICAM-1 has been identified as one of the host receptors for parasitized erythrocytes and has been implicated as being involved in progression to cerebral malaria. Thus...

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Autors principals: Craig, A, Pinches, R, Khan, S, Roberts, D, Turner, G, Newbold, C, Berendt, A
Format: Journal article
Idioma:English
Publicat: 1997