Role for cyclin-dependent kinase 2 in mitosis exit.
Mitosis requires cyclin-dependent kinase (cdk) 1-cyclin B activity [1]. Exit from mitosis depends on the inactivation of the complex by the degradation of cyclin B [2]. Cdk2 is also active during mitosis [3, 4]. In Xenopus egg extracts, cdk2 is primarily in complex with cyclin E, which is stable [5]...
Main Authors: | D'Angiolella, V, Costanzo, V, Gottesman, M, Avvedimento, E, Gautier, J, Grieco, D |
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Format: | Journal article |
Language: | English |
Published: |
2001
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