Role for cyclin-dependent kinase 2 in mitosis exit.

Mitosis requires cyclin-dependent kinase (cdk) 1-cyclin B activity [1]. Exit from mitosis depends on the inactivation of the complex by the degradation of cyclin B [2]. Cdk2 is also active during mitosis [3, 4]. In Xenopus egg extracts, cdk2 is primarily in complex with cyclin E, which is stable [5]...

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Príomhchruthaitheoirí: D'Angiolella, V, Costanzo, V, Gottesman, M, Avvedimento, E, Gautier, J, Grieco, D
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2001