The impact of chronic in vivo glucocorticoid excess on the functional characteristics of human skin fibroblasts obtained from patients with endogenous Cushing's syndrome.

The impact of chronic in vivo glucocorticoid excess on the functional characteristics of human skin fibroblasts obtained from patients with endogenous Cushing's syndrome.

OBJECTIVE: Chronic exposure to elevated glucocorticoid (GC) concentrations induces detrimental effects in several tissues. In the skin, GCs provoke intense alterations on various parameters of the physiology of fibroblasts, cumulatively leading to skin atrophy and impaired wound healing. As there a...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Zervolea, I, Pratsinis, H, Tsagarakis, S, Karavitaki, N, Stathakos, D, Thalassinos, N, Kletsas, D
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2005

Παρόμοια τεκμήρια

The Unexpected Anabolic Phenotype and Extended Longevity of Skin Fibroblasts after Chronic Glucocorticoid Excess
ανά: Harris Pratsinis, κ.ά.
Έκδοση: (2006-04-01)

Assessment of GH reserve before and after successful treatment of adult patients with Cushing's syndrome.
ανά: Tzanela, M, κ.ά.
Έκδοση: (2004)

Evaluation of bone mineral density of the peripheral skeleton in pre- and postmenopausal women with newly diagnosed endogenous Cushing's syndrome.
ανά: Karavitaki, N, κ.ά.
Έκδοση: (2004)

Evaluation of GH reserve in patients with adrenal incidentalomas and biochemical evidence of subclinical autonomous glucocorticoid hypersecretion.
ανά: Tzanela, M, κ.ά.
Έκδοση: (2005)

Coexistence of bone and vascular disturbances in patients with endogenous glucocorticoid excess
ανά: Chieko Yano, κ.ά.
Έκδοση: (2022-12-01)

Metformin and Bone Metabolism in Endogenous Glucocorticoid Excess: An Exploratory Study
ανά: Frederick Vogel, κ.ά.
Έκδοση: (2021-10-01)

E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess
ανά: Wei Zhang, κ.ά.
Έκδοση: (2023-11-01)

Mortality in Cushing's syndrome: systematic analysis of a large series with prolonged follow-up.
ανά: Ntali, G, κ.ά.
Έκδοση: (2013)

Challenges in the postsurgical recovery of cushing syndrome: glucocorticoid withdrawal syndrome
ανά: Catherine D. Zhang, κ.ά.
Έκδοση: (2024-04-01)

Glucocorticoid-induced osteoporosis: lessons from Cushing's syndrome.
ανά: Tóth, M, κ.ά.
Έκδοση: (2013)

Invasive fungal infections in endogenous Cushing’s syndrome
ανά: Rafael Selbach Scheffel, κ.ά.
Έκδοση: (2010-06-01)

Etomidate in the management of hypercortisolaemia in Cushing's syndrome: a review.
ανά: Preda, V, κ.ά.
Έκδοση: (2012)

Metabolic complications of endogenous Cushing: patient selection for screening
Έκδοση: (2013-03-01)

Activation of the JNKs/ATM-p53 axis is indispensable for the cytoprotection of dermal fibroblasts exposed to UVB radiation
ανά: Eleni Mavrogonatou, κ.ά.
Έκδοση: (2022-07-01)

Cushing’s glucocorticoid syndrome in the practice of a rheumatologist (A review of literature)
ανά: Azamat Makhmudovich Satybaldyev
Έκδοση: (2013-12-01)

The Effect of Chronic Glucocorticoid Exposure on Brown Adipose Tissue in Cushing’s Disease
ανά: Alev Selek, κ.ά.
Έκδοση: (2021-03-01)

Cushing’s syndrome with no clinical stigmata – a variant of glucocorticoid resistance syndrome
ανά: Ved V. Gossain, κ.ά.
Έκδοση: (2018-12-01)

Disturbed bone marrow adiposity in patients with Cushing’s syndrome and glucocorticoid- and postmenopausal- induced osteoporosis
ανά: Nina N. Sørensen, κ.ά.
Έκδοση: (2023-10-01)

The Regulation of Muscle Mass by Endogenous Glucocorticoids
ανά: Daniel L Marks, κ.ά.
Έκδοση: (2015-02-01)

Co-Occurrence of Exogenous and Endogenous Cushing’s Syndromes—Dilemma in Diagnosis
ανά: Chin Voon Tong, κ.ά.
Έκδοση: (2019-01-01)

Endogenous Obesity Associated with Cushing’s Disease: A Case Report
ανά: Müge Şahin, κ.ά.
Έκδοση: (2021-03-01)

Role of endogenous glucocorticoids in hyperalgesia and edema in old arthritic rats
ανά: C.M. Yokoro, κ.ά.
Έκδοση: (2003-01-01)

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.
ανά: Bentley, L, κ.ά.
Έκδοση: (2014)

An N-ethyl-n-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess
ανά: Bentley, L, κ.ά.
Έκδοση: (2014)

Modern Treatment of Cushing's Shows a High Cure Rate and a Low Mortality.
ανά: Ntali, G, κ.ά.
Έκδοση: (2010)

Decreased Trabecular Bone Score in Patients With Active Endogenous Cushing’s Syndrome
ανά: Barbara Stachowska, κ.ά.
Έκδοση: (2021-01-01)

Exogenous Cushing Syndrome: When do We Get the Benefit of Glucocorticoid Stress Dose?
ανά: Soebagijo Adi Soelistijo, κ.ά.
Έκδοση: (2020-09-01)

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.
ανά: Natalie Saini, κ.ά.
Έκδοση: (2016-10-01)

Choroidal thickness and retinal abnormalities by optical coherence tomography in endogenous Cushing’s syndrome
ανά: Maria Fernanda Abalem, κ.ά.
Έκδοση: (2016-12-01)

Adrenal Insufficiency under Standard Dosage of Glucocorticoid Replacement after Unilateral Adrenalectomy for Cushing’s Syndrome
ανά: Kentaro Fujii, κ.ά.
Έκδοση: (2016-01-01)

The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing’s disease and silent corticotroph tumors
ανά: Paulina Kober, κ.ά.
Έκδοση: (2023-03-01)

Clinical Characteristics of Endogenous Cushing’s Syndrome at a Medical Center in Southern Taiwan
ανά: Shih-Chen Tung, κ.ά.
Έκδοση: (2013-01-01)

Endogenous glucocorticoids in inflammation: contributions of systemic and local responses
ανά: Rowan S. Hardy, κ.ά.
Έκδοση: (2012-07-01)

Optogenetic elevation of endogenous glucocorticoid level in larval zebrafish
ανά: Rodrigo J De Marco, κ.ά.
Έκδοση: (2013-05-01)

Neurocognitive functions and brain volume in patients with endogenous cushing's syndrome before and after curative surgery
ανά: Nachimuthu Kumar, κ.ά.
Έκδοση: (2020-01-01)

AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome.
ανά: Christ-Crain, M, κ.ά.
Έκδοση: (2008)

Design and Synthesis of Novel Antioxidant 2-Substituted-5,7,8-Trimethyl-1,4-Benzoxazine Hybrids: Effects on Young and Senescent Fibroblasts
ανά: Theano Fotopoulou, κ.ά.
Έκδοση: (2024-06-01)

Therapy in endocrine disease: Etomidate in the management of hypercortisolaemia in Cushing's syndrome: A review (European Journal of Endocrinology 167, (137-143))
ανά: Preda, V, κ.ά.
Έκδοση: (2013)

Different Potent Glucocorticoids, Different Routes of Exposure but the Same Result: Iatrogenic Cushing’s Syndrome and Adrenal Insufficiency
ανά: Ayla Güven
Έκδοση: (2020-12-01)

Holistic burden of illness in patients with endogenous Cushing's syndrome: A systematic literature review
ανά: Gabrielle Page‐Wilson, κ.ά.
Έκδοση: (2024-01-01)