Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts.

Slični predmeti

• Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.
  od: Xu, S, i dr.
  Izdano: (2004)
• Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.
  od: Shi-Wen, X, i dr.
  Izdano: (2004)
• Response of human lung fibroblast cells to stimulation by endothelin-1: Involvement of ras/MEK/ERK and PI3 kinase
  od: Shiwen, X, i dr.
  Izdano: (2003)
• Bosentan alleviates the pro-fibrotic phenotype of lung scleroderma fibroblasts: Implications for treatment of scleroderma.
  od: Leask, A, i dr.
  Izdano: (2005)
• Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.
  od: Shi-wen, X, i dr.
  Izdano: (2007)