An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria.
<p><strong>Background:</strong> The artemisinins are potent and widely used antimalarial drugs that are eliminated rapidly. A simple concentration–effect pharmacometric model does not explain why dosing more frequently than once daily fails to augment parasite clearance and improve...
Những tác giả chính: | , , , , , , |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
Oxford University Press
2023
|