An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria.

<p><strong>Background:</strong> The artemisinins are potent and widely used antimalarial drugs that are eliminated rapidly. A simple concentration–effect pharmacometric model does not explain why dosing more frequently than once daily fails to augment parasite clearance and improve...

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Những tác giả chính: Saralamba, S, Simpson, JA, Choosri, N, White, L, Pan-Ngum, W, Dondorp, AM, White, NJ
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Oxford University Press 2023