Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families.

The gene coding for the amyloid protein, a component of neuritic plaques found in brain tissue from patients with Alzheimer's disease, has been localized to chromosome 21, and neighbouring polymorphic DNA markers segregate with Alzheimer's disease in several large families. These data, and...

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Bibliographic Details
Main Authors: Van Broeckhoven, C, Genthe, A, Vandenberghe, A, Horsthemke, B, Backhovens, H, Raeymaekers, P, Van Hul, W, Wehnert, A, Gheuens, J, Cras, P
Format: Journal article
Language:English
Published: 1987