Pancreatic L-Glutamine Administration Protects Pig Islets from Cold Ischemic Injury and Increases Resistance toward Inflammatory Mediators

Pancreatic L-Glutamine Administration Protects Pig Islets from Cold Ischemic Injury and Increases Resistance toward Inflammatory Mediators

The isolation and transplantation of porcine islets represent a future option for the treatment of type 1 diabetic patients. Stringent product release criteria and limited availability of transgenic and specific pathogen-free pigs will essentially require processing of explanted pig pancreata in spe...

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Xehetasun bibliografikoak
Egile Nagusiak:	Brandhorst, H, Theisinger, B, Guenther, B, Johnson, P, Brandhorst, D
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	SAGE Publications 2016

Antzeko izenburuak

Pancreatic L-Glutamine Administration Protects Pig Islets from Cold Ischemic Injury and Increases Resistance toward Inflammatory Mediators
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Quality of isolated pig islets is improved using perfluorohexyloctane for pancreas storage in a split lobe model.
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Quality of Isolated Pig Islets is Improved Using Perfluorohexyloctane for Pancreas Storage in a Split Lobe Model
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Pretransplant Induction of HSP-70 in Isolated Adult Pig Islets Decreases Early Islet Xenograft Survival
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Basement membrane proteins improve human islet survival in hypoxia: Implications for islet inflammation
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Effect of etanercept concentration on human islet integrity
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Pancreas storage in oxygenated perfluorodecalin does not restore post-transplant function of isolated pig islets pre-damaged by warm ischemia.
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High-dosed nicotinamide decreases early graft failure after pig to nude rat intraportal islet transplantation.
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Quantifying the effects of different neutral proteases on human islet integrity
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Degraded collagenase deteriorates islet viability.
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Adaption of neutral protease activity for islet isolation from the long-term two-layer method-stored pig pancreas.
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Induction and amelioration of environmental stress in isolated islets until transplantation
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High concentrations of Etanercept reduce human islet function and integrity
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High Concentrations of Etanercept Reduce Human Islet Function and Integrity
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Influence of collagenase loading on long-term preservation of pig pancreas by the two-layer method for subsequent islet isolation.
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Hyperthermic preconditioning protects pig islet grafts from early inflammation but enhances rejection in immunocompetent mice.
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Anti-caspase-3 preconditioning increases proinsulin secretion and deteriorates posttransplant function of isolated human islets
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Adjustment of the ratio between collagenase class II and I improves islet isolation outcome.
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