Advances in oligonucleotide drug delivery

Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these molecules have potential therapeutic applicat...

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Detalhes bibliográficos
Principais autores: Roberts, TC, Langer, R, Wood, MJA
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2020