Leveraging genome wide association studies and single cell RNA sequencing in inflammatory bowel disease

Leveraging genome wide association studies and single cell RNA sequencing in inflammatory bowel disease

In this thesis, the main scientific pursuit is that of leveraging information from genome-wide association studies (GWAS) in combination with gene expression datasets such as to narrow down the list of genes and cell-types that may be important for pharmacological targeting in heritable traits, part...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Voda, A-I
Andre forfattere:	Jostins-Dean, L
Format:	Thesis
Sprog:	English
Udgivet:	2022
Fag:	Genomics single cell sequencing GWAS Gene expression Inflammatory bowel diseases

Lignende værker

Associations of inflammatory cytokines with inflammatory bowel disease: a Mendelian randomization study
af: Zhaoxiang Song, et al.
Udgivet: (2024-01-01)

Sequencing-based genome-wide association studies reporting standards
af: Aoife McMahon, et al.
Udgivet: (2021-10-01)

Association between inflammatory bowel disease and interleukins, chemokines: a two-sample bidirectional mendelian randomization study
af: Guojiu Fang, et al.
Udgivet: (2023-05-01)

Two-sample Mendelian randomization analysis evaluates causal associations between inflammatory bowel disease and osteoporosis
af: Zhujiang Dai, et al.
Udgivet: (2023-05-01)

Exploring causal association between malnutrition, nutrients intake and inflammatory bowel disease: a Mendelian randomization analysis
af: Shi Wang, et al.
Udgivet: (2024-08-01)

RNA Modification in Inflammatory Bowel Diseases
af: Mika Nakayama, et al.
Udgivet: (2022-07-01)

Past, present, and future developments in single-step genomic models
af: Matias Bermann, et al.
Udgivet: (2022-12-01)

The landscape of miRNA-mRNA regulatory network and cellular sources in inflammatory bowel diseases: insights from text mining and single cell RNA sequencing analysis
af: Yuan Li, et al.
Udgivet: (2024-08-01)

Identifying Common Genetic Etiologies Between Inflammatory Bowel Disease and Related Immune-Mediated Diseases
af: Xianqiang Liu, et al.
Udgivet: (2024-11-01)

A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
af: Thomas, T
Udgivet: (2023)

scGWAS: landscape of trait-cell type associations by integrating single-cell transcriptomics-wide and genome-wide association studies
af: Peilin Jia, et al.
Udgivet: (2022-10-01)

Bowel Ultrasound in Inflammatory Bowel Disease: How Far in the Grayscale?
af: Federica Furfaro, et al.
Udgivet: (2021-07-01)

Immune mechanisms in inflammatory bowel disease/ [electronic book]
af: Blumberg, Richard S., et al.
Udgivet: (2006)

Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management
af: Martina Ledergerber, et al.
Udgivet: (2021-02-01)

Inflammatory bowel disease : an atlas of investigation and management /
af: Orchard, Timothy R. 534319
Udgivet: (2011)

The causal effect of inflammatory bowel disease on diffuse large B-cell lymphoma: two-sample Mendelian randomization study
af: Chuanyang Lu, et al.
Udgivet: (2023-08-01)

Inflammatory Bowel Disease and Thrombosis
af: Ahmet Tezel, et al.
Udgivet: (2012-05-01)

Angiogenesis and inflammatory bowel disease
af: Azzam Nahla
Udgivet: (2007-01-01)

Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease
af: Elisabeth Norén, et al.
Udgivet: (2017-05-01)

Providing LGBTQ+ affirming care to young adults with inflammatory bowel diseases
af: Cade Johnson, et al.
Udgivet: (2024-01-01)

Assessment of quality of life in patients with inflammatory bowel disease
af: Ives Alexandre Yutani Koseki, et al.
Udgivet: (2022-07-01)

Single-step genome-wide association study for susceptibility to Teratosphaeria nubilosa and precocity of vegetative phase change in Eucalyptus globulus
af: Marianella Quezada, et al.
Udgivet: (2023-07-01)

Molecular characterization and antibiotic resistance of Clostridioides difficile in patients with inflammatory bowel disease from two hospitals in China
af: Tao Lv, et al.
Udgivet: (2022-09-01)

Landscape of inflammatory bowel disease in Singapore
af: Daren Low, et al.
Udgivet: (2022-07-01)

Genome-wide association study provided insights into the polled phenotype and polled intersex syndrome (PIS) in goats
af: Fuhong Zhang, et al.
Udgivet: (2024-07-01)

Inflammatory bowel disease and rheumatoid arthritis share a common genetic structure
af: Guoling Cao, et al.
Udgivet: (2024-06-01)

Genome-Wide Study Updates in the International Genetics and Translational Research in Transplantation Network (iGeneTRAiN)
af: Claire E. Fishman, et al.
Udgivet: (2019-11-01)

Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease
af: Sanjay Mukherjee, et al.
Udgivet: (2019-05-01)

Mucosal Mast Cells in Irritable Bowel Syndrome and Inflammatory Bowel Disease
af: Bilge Tunc, et al.
Udgivet: (2005-01-01)

Altered splicing associated with the pathology of inflammatory bowel disease
af: Kiera Berger, et al.
Udgivet: (2021-07-01)

Inflammatory bowel disease and sarcopenia
af: Zhang Wendian
Udgivet: (2022-06-01)

Inflammatory bowel disease is causally related to irritable bowel syndrome: a bidirectional two-sample Mendelian randomization study
af: Haoran Ke, et al.
Udgivet: (2023-04-01)

Clinical Value of Inflammatory Bowel Disease Symptom Inventory in Evaluating the Activity of Inflammatory Bowel Disease
af: Zhanpeng LIU, Xiaozhong YANG, Mengxue CHEN, Menghui ZHANG, Honggang WANG
Udgivet: (2022-05-01)

Proinflammatory cytokines in irritable bowel syndrome: a comparison with inflammatory bowel disease
af: Antigony Mitselou, et al.
Udgivet: (2020-01-01)

Psychological characteristics of patients with functional and inflammatory bowel disorders
af: Kozlova I.V., et al.
Udgivet: (2014-03-01)

Optimized single-cell RNA sequencing protocol to study early genome activation in mammalian preimplantation development
af: Nina Boskovic, et al.
Udgivet: (2023-09-01)

Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources
af: Eleftherios Pilalis, et al.
Udgivet: (2025-03-01)

Iranian Registry of Crohn’s and Colitis: study profile of first nation-wide inflammatory bowel disease registry in Middle East
af: Masoud M Malekzadeh, et al.
Udgivet: (2019-07-01)

The landscape of rare genetic variation associated with inflammatory bowel disease and Parkinson’s disease comorbidity
af: Meltem Ece Kars, et al.
Udgivet: (2024-05-01)

Effect of Crocin on Inflammatory Bowel Diseases
af: Nastaran Rezaei, et al.
Udgivet: (2017-03-01)