Leveraging genome wide association studies and single cell RNA sequencing in inflammatory bowel disease

Leveraging genome wide association studies and single cell RNA sequencing in inflammatory bowel disease

In this thesis, the main scientific pursuit is that of leveraging information from genome-wide association studies (GWAS) in combination with gene expression datasets such as to narrow down the list of genes and cell-types that may be important for pharmacological targeting in heritable traits, part...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Voda, A-I
Rannpháirtithe:	Jostins-Dean, L
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2022
Ábhair:	Genomics single cell sequencing GWAS Gene expression Inflammatory bowel diseases

Míreanna comhchosúla

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Immune mechanisms in inflammatory bowel disease/ [electronic book]
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Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management
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The causal effect of inflammatory bowel disease on diffuse large B-cell lymphoma: two-sample Mendelian randomization study
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Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease
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Assessment of quality of life in patients with inflammatory bowel disease
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Molecular characterization and antibiotic resistance of Clostridioides difficile in patients with inflammatory bowel disease from two hospitals in China
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Landscape of inflammatory bowel disease in Singapore
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Genome-Wide Study Updates in the International Genetics and Translational Research in Transplantation Network (iGeneTRAiN)
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Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease
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Mucosal Mast Cells in Irritable Bowel Syndrome and Inflammatory Bowel Disease
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Altered splicing associated with the pathology of inflammatory bowel disease
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Inflammatory bowel disease and sarcopenia
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Inflammatory bowel disease is causally related to irritable bowel syndrome: a bidirectional two-sample Mendelian randomization study
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Clinical Value of Inflammatory Bowel Disease Symptom Inventory in Evaluating the Activity of Inflammatory Bowel Disease
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Proinflammatory cytokines in irritable bowel syndrome: a comparison with inflammatory bowel disease
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Foilsithe / Cruthaithe: (2020-01-01)

Psychological characteristics of patients with functional and inflammatory bowel disorders
de réir: Kozlova I.V., et al.
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Optimized single-cell RNA sequencing protocol to study early genome activation in mammalian preimplantation development
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Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources
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Iranian Registry of Crohn’s and Colitis: study profile of first nation-wide inflammatory bowel disease registry in Middle East
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The landscape of rare genetic variation associated with inflammatory bowel disease and Parkinson’s disease comorbidity
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Effect of Crocin on Inflammatory Bowel Diseases
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