Structural/mechanistic insights into the efficacy of nonclassical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates

Structural/mechanistic insights into the efficacy of nonclassical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates

Clavulanic acid and avibactam are clinically deployed serine β-lactamase inhibitors, important as a defence against antibacterial resistance. Bicyclic boronates are recently discovered inhibitors of serine and some metallo β-lactamases. Here, we show that avibactam and a bicyclic boronate inhibit L2...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Calvopiña, K, Hinchliffe, P, Brem, J, Heesom, K, Johnson, S, Cain, R, Lohans, C, Fishwick, C, Schofield, C, Spencer, J, Avison, M
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Wiley 2017

Míreanna comhchosúla

Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates.
de réir: Calvopiña, K, et al.
Foilsithe / Cruthaithe: (2016)

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates
de réir: Cahill, S, et al.
Foilsithe / Cruthaithe: (2019)

Mechanistic insights into β-lactamase-catalysed carbapenem degradation through product characterisation
de réir: Lohans, C, et al.
Foilsithe / Cruthaithe: (2019)

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
de réir: Brem, J, et al.
Foilsithe / Cruthaithe: (2016)

Cyclic Boronates Inhibit All Classes of β-Lactamase.
de réir: Cahill, S, et al.
Foilsithe / Cruthaithe: (2017)

Profiling interactions of vaborbactam with metallo-β-lactamases
de réir: Langley, G, et al.
Foilsithe / Cruthaithe: (2019)

Faropenem reacts with serine and metallo-β-lactamases to give multiple products
de réir: Lucic, A, et al.
Foilsithe / Cruthaithe: (2021)

Stenotrophomonas maltophilia in Salad
de réir: Andleeb Qureshi, et al.
Foilsithe / Cruthaithe: (2005-07-01)

New Delhi metallo-beta-lactamase 1 catalyzes avibactam and aztreonam hydrolysis
de réir: Lohans, C, et al.
Foilsithe / Cruthaithe: (2017)

New Delhi metallo-β-lactamase-1 catalyses avibactam and aztreonam hydrolysis.
de réir: Lohans, C, et al.
Foilsithe / Cruthaithe: (2017)

Effect of Stenotrophomonas maltophilia on Tuberculosis
de réir: Yue Li, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Stenotrophomonas maltophilia: An emerging pathogen in sepsis
de réir: J S Soumya, et al.
Foilsithe / Cruthaithe: (2020-01-01)

Investigation of Metallo-beta-lactamase Genes (L1 and NDM1) in Isolates of Stenotrophomonas maltophilia
de réir: Rabeeh Izadi Amoli, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Clinical ineffectiveness of latamoxef for Stenotrophomonas maltophilia infection
de réir: Hagiya H, et al.
Foilsithe / Cruthaithe: (2015-10-01)

Treatment of Stenotrophomonas maltophilia meningoencephalitis with intraventricular colistin
de réir: V. Romero Díaz-Maroto, et al.
Foilsithe / Cruthaithe: (2014-05-01)

Stenotrophomonas maltophilia endophthalmitis following keratoplasty
de réir: Bilge Tarım, et al.
Foilsithe / Cruthaithe: (2023-10-01)

Assay platform for clinically relevant metallo-β-lactamases.
de réir: van Berkel, S, et al.
Foilsithe / Cruthaithe: (2013)

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
de réir: Jürgen Brem, et al.
Foilsithe / Cruthaithe: (2016-08-01)

Correlating mutated ampC gene expression with ampc beta-lactamase hydrolysis activity in stenotrophomonas maltophilia
de réir: Shit, Chong Seng
Foilsithe / Cruthaithe: (2014)

Phenotypic heterogeneity affects Stenotrophomonas maltophilia K279a colony morphotypes and β-lactamase expression
de réir: Ebrahim Mama Abda, et al.
Foilsithe / Cruthaithe: (2015-12-01)

Prevalence and Detection of Stenotrophomonas maltophilia Carrying Metallo-β-lactamase blaL1 in Beijing, China
de réir: Zhan eYang, et al.
Foilsithe / Cruthaithe: (2014-12-01)

13 C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions
de réir: Lohans, C, et al.
Foilsithe / Cruthaithe: (2017)

Putative iron acquisition systems in Stenotrophomonas maltophilia
de réir: Vasodavan, Kalidasan, et al.
Foilsithe / Cruthaithe: (2018)

Elucidating pathogenic determinants in stenotrophomonas maltophilia pathogenesis
de réir: Thomas, Renjan
Foilsithe / Cruthaithe: (2014)

Stenotrophomonas maltophilia – A Threatening Nosocomial Pathogen
de réir: Ruchita Gawande, et al.
Foilsithe / Cruthaithe: (2024-12-01)

Stenotrophomonas maltophilia İzolatlarının Trimetoprim-sülfometaksazol Direnci
de réir: Filiz Orak, et al.
Foilsithe / Cruthaithe: (2021-06-01)

Stenotrophomonas maltophilia pneumonia in a premature infant
de réir: H Ozkan, et al.
Foilsithe / Cruthaithe: (1999-04-01)

Evaluation of Practice Changes in Therapy for Stenotrophomonas maltophilia
de réir: Alex Peterson-Weber, et al.
Foilsithe / Cruthaithe: (2024-07-01)

The epidemiology of Stenotrophomonas maltophilia and Achromobacter xylosoxidans infections
de réir: Shani Zilberman-Itskovich, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Stenotrophomonas maltophilia virulence: a current view
de réir: Vladimir Mikhailovich, et al.
Foilsithe / Cruthaithe: (2024-04-01)

Stenotrophomonas maltophilia – Clinical Significance, Treatment of Infections
de réir: Nowicka Joanna, et al.
Foilsithe / Cruthaithe: (2023-11-01)

Molecular-genetic portrait of virulence of Stenotrophomonas maltophilia
de réir: Vladimir M. Mikhailovich, et al.
Foilsithe / Cruthaithe: (2023-11-01)

Stenotrophomonas maltophilia in Lower Respiratory Tract Infections
de réir: Kiran Chawla, et al.
Foilsithe / Cruthaithe: (2014-12-01)

tet-Dependent Gene Expression in Stenotrophomonas maltophilia
de réir: Rebecca Horch, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Stenotrophomonas maltophilia: Complicating treatment of ESBL UTI
de réir: Simit Kumar, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Putative Iron Acquisition Systems in Stenotrophomonas maltophilia
de réir: V. Kalidasan, et al.
Foilsithe / Cruthaithe: (2018-08-01)

Stenotrophomonas maltophilia: An emerging entity for cluster endophthalmitis
de réir: Sarita Beri, et al.
Foilsithe / Cruthaithe: (2017-01-01)

Stenotrophomonas maltophilia: An uncommon cause of liver abscess
de réir: Srujana Mohanty, et al.
Foilsithe / Cruthaithe: (2021-01-01)

Stenotrophomonas maltophilia mimicking Klebsiella on Chromogenic Media
de réir: Vivek Hada, et al.
Foilsithe / Cruthaithe: (2017-10-01)

Antifungal activity of Stenotrophomonas maltophilia in Stomoxys calcitranslarvae
de réir: Ana Paula Rodrigues Moraes, et al.