Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.

FIH (Factor inhibiting hypoxia-inducible factor), an asparaginyl beta-hydroxylase belonging to the super-family of 2-oxoglutarate and Fe(II)-dependent dioxygenases, catalyses hydroxylation of Asn-803 of hypoxia-inducible factor, a transcription factor that regulates the mammalian hypoxic response. O...

书目详细资料
Main Authors:	Lancaster, D, McDonough, M, Schofield, C
格式:	Journal article
语言:	English
出版:	2004

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