Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.
FIH (Factor inhibiting hypoxia-inducible factor), an asparaginyl beta-hydroxylase belonging to the super-family of 2-oxoglutarate and Fe(II)-dependent dioxygenases, catalyses hydroxylation of Asn-803 of hypoxia-inducible factor, a transcription factor that regulates the mammalian hypoxic response. O...
Váldodahkkit: | , , |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2004
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