Orexin excites GABAergic neurons of the arcuate nucleus by activating the sodium--calcium exchanger.
The neuropeptides orexins/hypocretins are essential for normal wakefulness and energy balance, and disruption of their function causes narcolepsy and obesity. Although much is known of the role of orexins in sleep/wake behavior, it remains unclear how they stimulate feeding and metabolism. One of th...
المؤلفون الرئيسيون: | Burdakov, D, Liss, B, Ashcroft, F |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2003
|
مواد مشابهة
-
Different effects of insulin on electrically distinct hypothalamic arcuate nucleus (ARC) neurones
حسب: Burdakov, D, وآخرون
منشور في: (2002) -
Cholecystokinin tunes firing of an electrically distinct subset of arcuate nucleus neurons by activating A-Type potassium channels.
حسب: Burdakov, D, وآخرون
منشور في: (2002) -
Targeting the T-type calcium channel Cav3.2 in GABAergic arcuate nucleus neurons to treat obesity
حسب: Bing Feng, وآخرون
منشور في: (2021-12-01) -
Low-voltage-activated A-current controls the firing dynamics of mouse hypothalamic orexin neurons.
حسب: Burdakov, D, وآخرون
منشور في: (2004) -
Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin.
حسب: Ma, X, وآخرون
منشور في: (2007)