Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.

The identification of susceptibility genes for human disease is a major goal of current biomedical research. Both sequence and structural variation have emerged as major genetic sources of phenotypic variability and growing evidence points to copy number variation as a particularly important source...

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Bibliographic Details
Main Authors: Ermakova, O, Piszczek, L, Luciani, L, Cavalli, F, Ferreira, T, Farley, D, Rizzo, S, Paolicelli, R, Al-Banchaabouchi, M, Nerlov, C, Moriggl, R, Luscombe, N, Gross, C
Format: Journal article
Language:English
Published: 2011