Selectivity in enrichment of cAMP-dependent protein kinase regulatory subunits type I and type II and their interactors using modified cAMP affinity resins.

Selectivity in enrichment of cAMP-dependent protein kinase regulatory subunits type I and type II and their interactors using modified cAMP affinity resins.

cAMP regulates cellular functions primarily by activating PKA. The involvement of PKAs in various signaling pathways occurring simultaneously in different cellular compartments necessitates stringent spatial and temporal regulation. This specificity is largely achieved by binding of PKA to protein s...

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Bibliographic Details
Main Authors: Aye, T, Mohammed, S, van den Toorn, H, van Veen, T, van der Heyden, MA, Scholten, A, Heck, A
Format: Journal article
Language:English
Published: 2009

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