Inert gas transport in blood and tissues.

This article establishes the basic mathematical models and the principles and assumptions used for inert gas transfer within body tissues-first, for a single compartment model and then for a multicompartment model. From these, and other more complex mathematical models, the transport of inert gases...

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Main Authors: Baker, AB, Farmery, A
Format: Book section
Published: 2011
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author Baker, AB
Farmery, A
author_facet Baker, AB
Farmery, A
author_sort Baker, AB
collection OXFORD
description This article establishes the basic mathematical models and the principles and assumptions used for inert gas transfer within body tissues-first, for a single compartment model and then for a multicompartment model. From these, and other more complex mathematical models, the transport of inert gases between lungs, blood, and other tissues is derived and compared to known experimental studies in both animals and humans. Some aspects of airway and lung transfer are particularly important to the uptake and elimination of inert gases, and these aspects of gas transport in tissues are briefly described. The most frequently used inert gases are those that are administered in anesthesia, and the specific issues relating to the uptake, transport, and elimination of these gases and vapors are dealt with in some detail showing how their transfer depends on various physical and chemical attributes, particularly their solubilities in blood and different tissues. Absorption characteristics of inert gases from within gas cavities or tissue bubbles are described, and the effects other inhaled gas mixtures have on the composition of these gas cavities are discussed. Very brief consideration is given to the effects of hyper- and hypobaric conditions on inert gas transport.
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spelling oxford-uuid:cf3d2bdd-a56f-4a70-a31e-c93ec8154b2e2022-03-27T07:41:06ZInert gas transport in blood and tissues.Book sectionhttp://purl.org/coar/resource_type/c_3248uuid:cf3d2bdd-a56f-4a70-a31e-c93ec8154b2eSymplectic Elements at Oxford2011Baker, ABFarmery, AThis article establishes the basic mathematical models and the principles and assumptions used for inert gas transfer within body tissues-first, for a single compartment model and then for a multicompartment model. From these, and other more complex mathematical models, the transport of inert gases between lungs, blood, and other tissues is derived and compared to known experimental studies in both animals and humans. Some aspects of airway and lung transfer are particularly important to the uptake and elimination of inert gases, and these aspects of gas transport in tissues are briefly described. The most frequently used inert gases are those that are administered in anesthesia, and the specific issues relating to the uptake, transport, and elimination of these gases and vapors are dealt with in some detail showing how their transfer depends on various physical and chemical attributes, particularly their solubilities in blood and different tissues. Absorption characteristics of inert gases from within gas cavities or tissue bubbles are described, and the effects other inhaled gas mixtures have on the composition of these gas cavities are discussed. Very brief consideration is given to the effects of hyper- and hypobaric conditions on inert gas transport.
spellingShingle Baker, AB
Farmery, A
Inert gas transport in blood and tissues.
title Inert gas transport in blood and tissues.
title_full Inert gas transport in blood and tissues.
title_fullStr Inert gas transport in blood and tissues.
title_full_unstemmed Inert gas transport in blood and tissues.
title_short Inert gas transport in blood and tissues.
title_sort inert gas transport in blood and tissues
work_keys_str_mv AT bakerab inertgastransportinbloodandtissues
AT farmerya inertgastransportinbloodandtissues