The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.

The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.

Microscopic polyangiitis is an autoimmune small-vessel vasculitis that often manifests as focal and necrotizing glomerulonephritis and renal failure. Antineutrophil cytoplasmic Abs (ANCAs) specific for myeloperoxidase (MPO) play a role in this disease, but the role of autoreactive MPO-specific CD4(+...

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Dettagli Bibliografici
Autori principali:	Ooi, J, Chang, J, Hickey, M, Borza, D, Fugger, L, Holdsworth, SR, Kitching, A
Natura:	Journal article
Lingua:	English
Pubblicazione:	2012

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