Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

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Objective: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system associated with pathogenic autoantibodies against the astrocyte water channel protein aquaporin-4 (AQP4). The presence of neutrophils is a characteristic feature in NMO lesions in humans. Neu...

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Hlavní autoři: Saadoun, S, Waters, P, MacDonald, C, Bell, B, Vincent, A, Verkman, A, Papadopoulos, M
Médium: Journal article
Jazyk:English
Vydáno: 2012

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