Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

Objective: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system associated with pathogenic autoantibodies against the astrocyte water channel protein aquaporin-4 (AQP4). The presence of neutrophils is a characteristic feature in NMO lesions in humans. Neu...

Повний опис

Бібліографічні деталі
Автори: Saadoun, S, Waters, P, MacDonald, C, Bell, B, Vincent, A, Verkman, A, Papadopoulos, M
Формат: Journal article
Мова:English
Опубліковано: 2012