XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.

XRCC1 is a scaffold protein that interacts with several DNA repair proteins and plays a critical role in DNA base excision repair (BER). XRCC1 protein is in a tight complex with DNA ligase IIIalpha (Lig III) and this complex is involved in the ligation step of both BER and repair of DNA single stran...

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Bibliografiska uppgifter
Huvudupphovsmän:	Parsons, J, Dianova, I, Finch, D, Tait, P, Ström, C, Helleday, T, Dianov, G
Materialtyp:	Journal article
Språk:	English
Publicerad:	2010

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